Cristiano Luis Dias
Dr. Dias joined the Department of Physics at NJIT as an Assistant Professor. Previously, he held a Post-doctoral position at Freie Universitat Berlin (Volkswagen foundation), University of Toronto, and Western University.
The focus of his research is in understanding fundamental problems in molecular Bio-Physics using large scale computer simulations. He is working towards understanding molecular mechanisms accounting for protein function, stability, and aggregation. These efforts are of paramount importance for the design of new drugs, to treat diseases that result from misfolding and/or aggregation, and to understand biological and cellular functions at the molecular level.
· PhD, Physics, McGill University.
· MSc, Physics, Universite de Montreal.
· Bsc, Physics, Universidade de Brasilia.
Dr. Dias uses theory and computer simulations to understand emerging phenomena at the interface of Physics, Biology, and Chemistry. His group uses all-atom models and develops coarse-grained models to study equilibrium and non-equilibrium phenomena in molecular Bio-Physics. Dr. Dias seeks to decipher: (i) microscopic mechanisms accounting for the aggregation of peptides into amyloid fibrils, (ii) how these fibrils interact with each other accounting for the bulk properties of biomaterials, and (iii) how they interact with micelles/cells. These efforts are of paramount importance for the design of new drugs to treat diseases that result from misfolding and/or aggregation, to understand biological and cellular functions at the molecular level, and to design new biomaterials.
Srinivasa R. Jampani, Farbood Mahmoudinobar, Zhaoqian Su and Cristiano L. Dias, Thermodynamics of Abeta16-21 dissociation from a fibril, PROTEIN: Structure, Function, and Bioinformatics 83:1963 (2015).
Cristiano L. Dias and Hue Sun Chan. Pressure-Dependence Properties of Elementary Hydrophobic Interactions: Ramifications for Activation Properties of Protein Folding. J. Phys. Chem. B 118 , 7488 (2014).
Chitra Narayanan and Cristiano L. Dias. Hydrophobic interactions and hydrogen bonds in beta-sheet formation. J. Chem. Phys. 139, 115103 (2013).